The WNT1 G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV

The WNT1 G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV

Abstract The recent identification of homozygous WNT1 mutations in individuals with osteogenesis imperfecta type XV (OI-XV) has suggested that WNT1 is a key ligand promoting the differentiation and function of bone-forming osteoblasts. Although such an influence was supported by subsequent studies,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nele Vollersen, Wenbo Zhao, Tim Rolvien, Fabiola Lange, Felix Nikolai Schmidt, Stephan Sonntag, Doron Shmerling, Simon von Kroge, Kilian Elia Stockhausen, Ahmed Sharaf, Michaela Schweizer, Meliha Karsak, Björn Busse, Ernesto Bockamp, Oliver Semler, Michael Amling, Ralf Oheim, Thorsten Schinke, Timur Alexander Yorgan
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
Sujets:
Biology (General)
QH301-705.5
Physiology
QP1-981
Accès en ligne:https://doaj.org/article/dec15195222f43c6a21a6c77c8ffa7fd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/dec15195222f43c6a21a6c77c8ffa7fd

Documents similaires