Serotonin deficiency induced after brain maturation rescues consequences of early life adversity

Abstract Brain serotonin (5-HT) system dysfunction is implicated in depressive disorders and acute depletion of 5-HT precursor tryptophan has frequently been used to model the influence of 5-HT deficiency on emotion regulation. Tamoxifen (TAM)-induced Cre/loxP-mediated inactivation of the tryptophan...

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Autores principales: B. Aboagye, T. Weber, H. L. Merdian, D. Bartsch, K. P. Lesch, J. Waider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dec780cc9c21464bb2794b7d93a46140
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