Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9

Bacteria lack the same suite of CRISPR tools that have been developed for mammalian cells. Here, the authors link aptamers to sgRNAs to allow small molecule control of gene editing in E. coli.

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Autores principales: Roman S. Iwasaki, Bagdeser A. Ozdilek, Andrew D. Garst, Alaksh Choudhury, Robert T. Batey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ded3f93171cd4f4bb57d5a441ed60ade
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