Mass Spectrometry as a Tool to Enhance “-omics” Education

The rise of "-omics" related technologies makes it essential for students to have experience working with large bioinformatics data sets. Although”-omic” datasets are complex and abstract, effective instruction can be improved when students see the direct connections between the data on a...

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Autores principales:	Michael J. Wolyniak, Nathan S. Reyna, Ruth Plymale, Welkin H. Pope, Daniel E. Westholm
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	Special aspects of education LC8-6691 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ded50bb8531f493896dc60b3fdc28f16
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spelling	oai:doaj.org-article:ded50bb8531f493896dc60b3fdc28f162021-11-15T15:04:53ZMass Spectrometry as a Tool to Enhance “-omics” Education10.1128/jmbe.v19i1.14591935-78851935-7877https://doaj.org/article/ded50bb8531f493896dc60b3fdc28f162018-03-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/jmbe.v19i1.1459https://doaj.org/toc/1935-7877https://doaj.org/toc/1935-7885The rise of "-omics" related technologies makes it essential for students to have experience working with large bioinformatics data sets. Although”-omic” datasets are complex and abstract, effective instruction can be improved when students see the direct connections between the data on a computer screen and the results of "wet lab" experimentation. Here we describe the use of protein mass spectrometry as a means for students to gain experience in connecting bioinformatic data with work done at the lab bench. Course-based Research Experiences (CREs) based on these techniques are accessible to institutions of all types as a result of rapidly declining costs for whole genome and proteome analysis. Our implementation is within a CRE based on viral infection of a bacterial host; however, this basic paradigm may be applied to other experimental systems of interest.Michael J. WolyniakNathan S. ReynaRuth PlymaleWelkin H. PopeDaniel E. WestholmAmerican Society for MicrobiologyarticleSpecial aspects of educationLC8-6691Biology (General)QH301-705.5ENJournal of Microbiology & Biology Education, Vol 19, Iss 1 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Special aspects of education LC8-6691 Biology (General) QH301-705.5
spellingShingle	Special aspects of education LC8-6691 Biology (General) QH301-705.5 Michael J. Wolyniak Nathan S. Reyna Ruth Plymale Welkin H. Pope Daniel E. Westholm Mass Spectrometry as a Tool to Enhance “-omics” Education
description	The rise of "-omics" related technologies makes it essential for students to have experience working with large bioinformatics data sets. Although”-omic” datasets are complex and abstract, effective instruction can be improved when students see the direct connections between the data on a computer screen and the results of "wet lab" experimentation. Here we describe the use of protein mass spectrometry as a means for students to gain experience in connecting bioinformatic data with work done at the lab bench. Course-based Research Experiences (CREs) based on these techniques are accessible to institutions of all types as a result of rapidly declining costs for whole genome and proteome analysis. Our implementation is within a CRE based on viral infection of a bacterial host; however, this basic paradigm may be applied to other experimental systems of interest.
format	article
author	Michael J. Wolyniak Nathan S. Reyna Ruth Plymale Welkin H. Pope Daniel E. Westholm
author_facet	Michael J. Wolyniak Nathan S. Reyna Ruth Plymale Welkin H. Pope Daniel E. Westholm
author_sort	Michael J. Wolyniak
title	Mass Spectrometry as a Tool to Enhance “-omics” Education
title_short	Mass Spectrometry as a Tool to Enhance “-omics” Education
title_full	Mass Spectrometry as a Tool to Enhance “-omics” Education
title_fullStr	Mass Spectrometry as a Tool to Enhance “-omics” Education
title_full_unstemmed	Mass Spectrometry as a Tool to Enhance “-omics” Education
title_sort	mass spectrometry as a tool to enhance “-omics” education
publisher	American Society for Microbiology
publishDate	2018
url	https://doaj.org/article/ded50bb8531f493896dc60b3fdc28f16
work_keys_str_mv	AT michaeljwolyniak massspectrometryasatooltoenhanceomicseducation AT nathansreyna massspectrometryasatooltoenhanceomicseducation AT ruthplymale massspectrometryasatooltoenhanceomicseducation AT welkinhpope massspectrometryasatooltoenhanceomicseducation AT danielewestholm massspectrometryasatooltoenhanceomicseducation
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Mass Spectrometry as a Tool to Enhance “-omics” Education

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