Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1

Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1

Abstract Early acute kidney injury (AKI) contributes to severe morbidity and mortality in critically burned patients. Renal inflammation plays a vital role in the progression of early AKI, acting as a therapeutic target. Astaxanthin (ATX) is a strong antioxidant widely distributed in marine organism...

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Détails bibliographiques
Auteurs principaux: Songxue Guo, Linsen Guo, Quan Fang, Meirong Yu, Liping Zhang, Chuangang You, Xingang Wang, Yong Liu, Chunmao Han
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/dee0bf589b3d41e599fea9404c283c05
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https://doaj.org/article/dee0bf589b3d41e599fea9404c283c05

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