A comparative molecular dynamics study of methylation state specificity of JMJD2A.

Histone modifications have great importance in epigenetic regulation. JMJD2A is a histone demethylase which is selective for di- and trimethyl forms of residues Lys9 and Lys36 of Histone 3 tail (H3K9 and H3K36). We present a molecular dynamics simulations of mono-, di- and trimethylated histone tail...

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Autores principales: Ozlem Ulucan, Ozlem Keskin, Burak Erman, Attila Gursoy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/dee6f486f34b4a0fa70c73da106466a3
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