A comparative molecular dynamics study of methylation state specificity of JMJD2A.
Histone modifications have great importance in epigenetic regulation. JMJD2A is a histone demethylase which is selective for di- and trimethyl forms of residues Lys9 and Lys36 of Histone 3 tail (H3K9 and H3K36). We present a molecular dynamics simulations of mono-, di- and trimethylated histone tail...
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Autores principales: | Ozlem Ulucan, Ozlem Keskin, Burak Erman, Attila Gursoy |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/dee6f486f34b4a0fa70c73da106466a3 |
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