Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation
Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...
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Main Authors: | Fanju W. Meng, Patrick J. Murphy |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/defecbbb3de94f43a44509e7439a4b62 |
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