The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.

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Bibliographic Details
Main Authors: Yijian Rao, Marco G. Perna, Benjamin Hofmann, Viola Beier, Thomas Wollert
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec06
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