The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.

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Autores principales: Yijian Rao, Marco G. Perna, Benjamin Hofmann, Viola Beier, Thomas Wollert
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec06
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spelling oai:doaj.org-article:df0bd52b826c4a808f835fa5eb6cec062021-12-02T14:38:54ZThe Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy10.1038/ncomms103382041-1723https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec062016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10338https://doaj.org/toc/2041-1723Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.Yijian RaoMarco G. PernaBenjamin HofmannViola BeierThomas WollertNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yijian Rao
Marco G. Perna
Benjamin Hofmann
Viola Beier
Thomas Wollert
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
description Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.
format article
author Yijian Rao
Marco G. Perna
Benjamin Hofmann
Viola Beier
Thomas Wollert
author_facet Yijian Rao
Marco G. Perna
Benjamin Hofmann
Viola Beier
Thomas Wollert
author_sort Yijian Rao
title The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
title_short The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
title_full The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
title_fullStr The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
title_full_unstemmed The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
title_sort atg1–kinase complex tethers atg9-vesicles to initiate autophagy
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec06
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AT violabeier theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy
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