The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.
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Nature Portfolio
2016
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oai:doaj.org-article:df0bd52b826c4a808f835fa5eb6cec062021-12-02T14:38:54ZThe Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy10.1038/ncomms103382041-1723https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec062016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10338https://doaj.org/toc/2041-1723Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles.Yijian RaoMarco G. PernaBenjamin HofmannViola BeierThomas WollertNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Yijian Rao Marco G. Perna Benjamin Hofmann Viola Beier Thomas Wollert The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
description |
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts recruits and tethers Atg9-vesicles. |
format |
article |
author |
Yijian Rao Marco G. Perna Benjamin Hofmann Viola Beier Thomas Wollert |
author_facet |
Yijian Rao Marco G. Perna Benjamin Hofmann Viola Beier Thomas Wollert |
author_sort |
Yijian Rao |
title |
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
title_short |
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
title_full |
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
title_fullStr |
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
title_full_unstemmed |
The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy |
title_sort |
atg1–kinase complex tethers atg9-vesicles to initiate autophagy |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/df0bd52b826c4a808f835fa5eb6cec06 |
work_keys_str_mv |
AT yijianrao theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT marcogperna theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT benjaminhofmann theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT violabeier theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT thomaswollert theatg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT yijianrao atg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT marcogperna atg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT benjaminhofmann atg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT violabeier atg1kinasecomplextethersatg9vesiclestoinitiateautophagy AT thomaswollert atg1kinasecomplextethersatg9vesiclestoinitiateautophagy |
_version_ |
1718390864476110848 |