A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.
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Main Authors: | Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su, Ying-Ting Chen, Michael S. Hershfield, Ming-Ta Michael Lee, Tian-Lu Cheng, Yuan-Tsong Chen, Steve R. Roffler, Jer-Yuarn Wu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/df2dcbdf3ece4077a9f03be585cdb8d7 |
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