Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain

Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain

The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.

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Autores principales: Jussi Kupari, Dmitry Usoskin, Marc Parisien, Daohua Lou, Yizhou Hu, Michael Fatt, Peter Lönnerberg, Mats Spångberg, Bengt Eriksson, Nikolaos Barkas, Peter V. Kharchenko, Karin Loré, Samar Khoury, Luda Diatchenko, Patrik Ernfors
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Q
Acceso en línea:https://doaj.org/article/df3a304dbc84446cb7fbb921b8b45840
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spelling oai:doaj.org-article:df3a304dbc84446cb7fbb921b8b458402021-12-02T15:52:37ZSingle cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain10.1038/s41467-021-21725-z2041-1723https://doaj.org/article/df3a304dbc84446cb7fbb921b8b458402021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21725-zhttps://doaj.org/toc/2041-1723The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.Jussi KupariDmitry UsoskinMarc ParisienDaohua LouYizhou HuMichael FattPeter LönnerbergMats SpångbergBengt ErikssonNikolaos BarkasPeter V. KharchenkoKarin LoréSamar KhouryLuda DiatchenkoPatrik ErnforsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jussi Kupari
Dmitry Usoskin
Marc Parisien
Daohua Lou
Yizhou Hu
Michael Fatt
Peter Lönnerberg
Mats Spångberg
Bengt Eriksson
Nikolaos Barkas
Peter V. Kharchenko
Karin Loré
Samar Khoury
Luda Diatchenko
Patrik Ernfors
Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
description The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.
format article
author Jussi Kupari
Dmitry Usoskin
Marc Parisien
Daohua Lou
Yizhou Hu
Michael Fatt
Peter Lönnerberg
Mats Spångberg
Bengt Eriksson
Nikolaos Barkas
Peter V. Kharchenko
Karin Loré
Samar Khoury
Luda Diatchenko
Patrik Ernfors
author_facet Jussi Kupari
Dmitry Usoskin
Marc Parisien
Daohua Lou
Yizhou Hu
Michael Fatt
Peter Lönnerberg
Mats Spångberg
Bengt Eriksson
Nikolaos Barkas
Peter V. Kharchenko
Karin Loré
Samar Khoury
Luda Diatchenko
Patrik Ernfors
author_sort Jussi Kupari
title Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_short Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_full Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_fullStr Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_full_unstemmed Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_sort single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/df3a304dbc84446cb7fbb921b8b45840
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