Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain

The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.

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Auteurs principaux:	Jussi Kupari, Dmitry Usoskin, Marc Parisien, Daohua Lou, Yizhou Hu, Michael Fatt, Peter Lönnerberg, Mats Spångberg, Bengt Eriksson, Nikolaos Barkas, Peter V. Kharchenko, Karin Loré, Samar Khoury, Luda Diatchenko, Patrik Ernfors
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/df3a304dbc84446cb7fbb921b8b45840
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spelling	oai:doaj.org-article:df3a304dbc84446cb7fbb921b8b458402021-12-02T15:52:37ZSingle cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain10.1038/s41467-021-21725-z2041-1723https://doaj.org/article/df3a304dbc84446cb7fbb921b8b458402021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21725-zhttps://doaj.org/toc/2041-1723The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.Jussi KupariDmitry UsoskinMarc ParisienDaohua LouYizhou HuMichael FattPeter LönnerbergMats SpångbergBengt ErikssonNikolaos BarkasPeter V. KharchenkoKarin LoréSamar KhouryLuda DiatchenkoPatrik ErnforsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jussi Kupari Dmitry Usoskin Marc Parisien Daohua Lou Yizhou Hu Michael Fatt Peter Lönnerberg Mats Spångberg Bengt Eriksson Nikolaos Barkas Peter V. Kharchenko Karin Loré Samar Khoury Luda Diatchenko Patrik Ernfors Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
description	The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different genetic susceptibilities for chronic pain.
format	article
author	Jussi Kupari Dmitry Usoskin Marc Parisien Daohua Lou Yizhou Hu Michael Fatt Peter Lönnerberg Mats Spångberg Bengt Eriksson Nikolaos Barkas Peter V. Kharchenko Karin Loré Samar Khoury Luda Diatchenko Patrik Ernfors
author_facet	Jussi Kupari Dmitry Usoskin Marc Parisien Daohua Lou Yizhou Hu Michael Fatt Peter Lönnerberg Mats Spångberg Bengt Eriksson Nikolaos Barkas Peter V. Kharchenko Karin Loré Samar Khoury Luda Diatchenko Patrik Ernfors
author_sort	Jussi Kupari
title	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_short	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_full	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_fullStr	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_full_unstemmed	Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
title_sort	single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/df3a304dbc84446cb7fbb921b8b45840
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Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain

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