Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.

In systems biology, a mathematical description of signal transduction processes is used to gain a more detailed mechanistic understanding of cellular signaling networks. Such models typically depend on a number of parameters that have different influence on the model behavior. Local sensitivity anal...

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Auteurs principaux: Yvonne Koch, Thomas Wolf, Peter K Sorger, Roland Eils, Benedikt Brors
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/df4bc1a8e8ea42eaa4c5063035f12ece
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