Development of a Chiral Capillary Electrophoresis Method for the Enantioseparation of Verapamil Using Cyclodextrins as Chiral Selectors and Experimental Design Optimization

Chirality is a property of asymmetry which determines the pharmacokinetic and pharmacological profiles of optically active pharmaceuticals. Verapamil (VER), a calcium channel blocker phenylalkylamine derivative used in the treatment of cardio-vascular diseases, is a chiral compound, marketed as a ra...

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Auteurs principaux: Melania Cârcu-Dobrin, Gabriel Hancu, Lajos Attila Papp, Ibolya Fülöp, Hajnal Kelemen
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/df69a0c708d14f3b9fef2dc0f7f54a08
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