Development of a Chiral Capillary Electrophoresis Method for the Enantioseparation of Verapamil Using Cyclodextrins as Chiral Selectors and Experimental Design Optimization
Chirality is a property of asymmetry which determines the pharmacokinetic and pharmacological profiles of optically active pharmaceuticals. Verapamil (VER), a calcium channel blocker phenylalkylamine derivative used in the treatment of cardio-vascular diseases, is a chiral compound, marketed as a ra...
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Auteurs principaux: | Melania Cârcu-Dobrin, Gabriel Hancu, Lajos Attila Papp, Ibolya Fülöp, Hajnal Kelemen |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/df69a0c708d14f3b9fef2dc0f7f54a08 |
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