An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export.

The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly. Intriguingly however, depletion of Aly only leads to a modest reduction in cellular mRNA nuclear export, suggesting the existence of addit...

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Autores principales: Brian R Jackson, James R Boyne, Marko Noerenberg, Adam Taylor, Guillaume M Hautbergue, Matthew J Walsh, Rachel Wheat, David J Blackbourn, Stuart A Wilson, Adrian Whitehouse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/df7aad35cc464e7fad144adaa0311cf6
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