An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export.
The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly. Intriguingly however, depletion of Aly only leads to a modest reduction in cellular mRNA nuclear export, suggesting the existence of addit...
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Autores principales: | Brian R Jackson, James R Boyne, Marko Noerenberg, Adam Taylor, Guillaume M Hautbergue, Matthew J Walsh, Rachel Wheat, David J Blackbourn, Stuart A Wilson, Adrian Whitehouse |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/df7aad35cc464e7fad144adaa0311cf6 |
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