The role of Candida albicans SPT20 in filamentation, biofilm formation and pathogenesis.

Candida albicans is a ubiquitous fungus, which can cause very serious and sometimes life-threatening infections in susceptible patients. We used Caenorhabditis elegans as a model host to screen a library of C. albicans mutants for decreased virulence and identified SPT20 as important for virulence....

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Bibliographic Details
Main Authors: Xiaojiang Tan, Beth Burgwyn Fuchs, Yan Wang, Weiping Chen, Grace J Yuen, Rosalyn B Chen, Elamparithi Jayamani, Cleo Anastassopoulou, Read Pukkila-Worley, Jeffrey J Coleman, Eleftherios Mylonakis
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
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Online Access:https://doaj.org/article/df867dbe221d406dadb9e8d2ec8e24c0
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