Role of hyperpolarization-activated cyclic nucleotide-gated ion channels in neuropathic pain: a proof-of-concept study of ivabradine in patients with chronic peripheral neuropathic pain
Abstract. Introduction:. Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels mediate repetitive action potential firing in the heart and nervous system. The HCN2 isoform is expressed in nociceptors, and preclinical studies suggest a critical role in neuropathic pain. Ivabradine is...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Wolters Kluwer
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/df891575fcf64e7b880192e384a1a0da |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|