Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila

In many animals, sperm DNA compaction is achieved by disulfide bonds between the sperm nuclear proteins that replace the histones. Here, the authors provide evidence that Drosophilamaternal thioredoxin Deadhead is required to unlock the sperm chromatin upon fertilization.

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Autores principales: Samantha Tirmarche, Shuhei Kimura, Raphaëlle Dubruille, Béatrice Horard, Benjamin Loppin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/df8965b2ee724451aa6eca8b14ec0737
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