Normalisation to blood activity is required for the accurate quantification of Na/I symporter ectopic expression by SPECT/CT in individual subjects.

The utilisation of the Na/I symporter (NIS) and associated radiotracers as a reporter system for imaging gene expression is now reaching the clinical setting in cancer gene therapy applications. However, a formal assessment of the methodology in terms of normalisation of the data still remains to be...

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Autores principales: Peggy Richard-Fiardo, Philippe R Franken, Audrey Lamit, Robert Marsault, Julien Guglielmi, Béatrice Cambien, Fanny Graslin, Sabine Lindenthal, Jacques Darcourt, Thierry Pourcher, Georges Vassaux
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/dfa96becc12d498889db584a921463ee
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