Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia

It is currently difficult to map DNA variants and surface phenotypes in the same cells, preventing direct linkage of phenotype and genotype. Here the authors report DAb-seq for simultaneous capture of DNA genotype and cell surface phenotype from single cells at high throughput.

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Auteurs principaux: Benjamin Demaree, Cyrille L. Delley, Harish N. Vasudevan, Cheryl A. C. Peretz, David Ruff, Catherine C. Smith, Adam R. Abate
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/dfb07e6143424db5a2a57dd7798d784c
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