Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia

It is currently difficult to map DNA variants and surface phenotypes in the same cells, preventing direct linkage of phenotype and genotype. Here the authors report DAb-seq for simultaneous capture of DNA genotype and cell surface phenotype from single cells at high throughput.

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Bibliographic Details
Main Authors: Benjamin Demaree, Cyrille L. Delley, Harish N. Vasudevan, Cheryl A. C. Peretz, David Ruff, Catherine C. Smith, Adam R. Abate
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Online Access:https://doaj.org/article/dfb07e6143424db5a2a57dd7798d784c
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