The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved.

Coordinated replication of eukaryotic genomes is intrinsically asymmetric, with continuous leading strand synthesis preceding discontinuous lagging strand synthesis. Here we provide two types of evidence indicating that, in fission yeast, these two biosynthetic tasks are performed by two different r...

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Autores principales: Izumi Miyabe, Thomas A Kunkel, Antony M Carr
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/dfb36560d8a845ea839967e4cf30f3e6
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