The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved.

Coordinated replication of eukaryotic genomes is intrinsically asymmetric, with continuous leading strand synthesis preceding discontinuous lagging strand synthesis. Here we provide two types of evidence indicating that, in fission yeast, these two biosynthetic tasks are performed by two different r...

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Auteurs principaux: Izumi Miyabe, Thomas A Kunkel, Antony M Carr
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/dfb36560d8a845ea839967e4cf30f3e6
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