A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9
Abstract Background Von Willebrand Disease (VWD) is the most common inherited bleeding disorder, caused by quantitative and qualitative changes in von Willebrand factor (VWF). The biology of VWD, studied in canine, porcine, and murine models, differ in species‐specific biology of VWF and the amenabi...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Wiley
2020
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| Accès en ligne: | https://doaj.org/article/dfb6426d17994ee9ae5dbf1dce097efe |
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