Constructing germline research cohorts from the discarded reads of clinical tumor sequences

Abstract Background Hundreds of thousands of cancer patients have had targeted (panel) tumor sequencing to identify clinically meaningful mutations. In addition to improving patient outcomes, this activity has led to significant discoveries in basic and translational domains. However, the targeted n...

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Bibliographic Details
Main Authors: Alexander Gusev, Stefan Groha, Kodi Taraszka, Yevgeniy R. Semenov, Noah Zaitlen
Format: article
Language:EN
Published: BMC 2021
Subjects:
R
Online Access:https://doaj.org/article/dfd1ed628f8e4314b50a12954fd90ff0
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