Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway

Expansion of visceral white adipose tissue (vWAT) occurs in response to nutrient excess, and is a risk factor for metabolic disease. SPRY1, a feedback inhibitor of receptor tyrosine kinase (RTK) signaling, is expressed in PDGFRa+ adipocyte progenitor cells (APC) in vivo. Global deficiency of Spry1 i...

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Autores principales: Xuehui Yang, Shivangi Pande, Robert A. Koza, Robert Friesel
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
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Acceso en línea:https://doaj.org/article/dfd1f8d43a5c4d89876a7a582db6fd13
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