Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
Topologically associating domains (TADs) detected by Hi-C technologies are megabase-scale areas of highly interacting chromatin. Here Gong, Lazaris et al. develop a computational approach to improve the reproducibility of Hi-C contact matrices and stratify TAD boundaries based on their insulating st...
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2018
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/dfd9fb5d66e34649a38ccc25f7137c60 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|