Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.

Characterizing the activating and inhibiting effect of protein-protein interactions (PPI) is fundamental to gain insight into the complex signaling system of a human cell. A plethora of methods has been suggested to infer PPI from data on a large scale, but none of them is able to characterize the e...

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Bibliographic Details
Main Authors: Apichat Suratanee, Martin H Schaefer, Matthew J Betts, Zita Soons, Heiko Mannsperger, Nathalie Harder, Marcus Oswald, Markus Gipp, Ellen Ramminger, Guillermo Marcus, Reinhard Männer, Karl Rohr, Erich Wanker, Robert B Russell, Miguel A Andrade-Navarro, Roland Eils, Rainer König
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/e01205940d804bc0bcc38759f7abd7ed
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https://doaj.org/article/e01205940d804bc0bcc38759f7abd7ed

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