Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease

Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease

Cerebrospinal fluid (CSF) p-tau181 (tau phosphorylated at threonine 181) is an established biomarker of Alzheimer’s disease (AD) reflecting abnormal tau metabolism in the AD brain. Here the authors demonstrate that CSF p-tau217 shows better performance as an AD biomarker than p-tau181.

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Detalles Bibliográficos
Autores principales: Shorena Janelidze, Erik Stomrud, Ruben Smith, Sebastian Palmqvist, Niklas Mattsson, David C. Airey, Nicholas K. Proctor, Xiyun Chai, Sergey Shcherbinin, John R. Sims, Gallen Triana-Baltzer, Clara Theunis, Randy Slemmon, Marc Mercken, Hartmuth Kolb, Jeffrey L. Dage, Oskar Hansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
Q
Acceso en línea:https://doaj.org/article/e021f91d669745fe90cd9b4d834f6303
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https://doaj.org/article/e021f91d669745fe90cd9b4d834f6303

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