TMEM16K is an interorganelle regulator of endosomal sorting

The endolysosomal pathway plays an important role in regulating protein and lipid sorting and degradation. Here, the authors show that TMEM16K, an endoplasmic reticulum lipid scramblase, forms ER-endosome contact sites where it regulates endosomal sorting.

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Autores principales: Maja Petkovic, Juan Oses-Prieto, Alma Burlingame, Lily Yeh Jan, Yuh Nung Jan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e026443ef1f54cb589f59433ef9e4058
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