TMEM16K is an interorganelle regulator of endosomal sorting

The endolysosomal pathway plays an important role in regulating protein and lipid sorting and degradation. Here, the authors show that TMEM16K, an endoplasmic reticulum lipid scramblase, forms ER-endosome contact sites where it regulates endosomal sorting.

Guardado en:
Detalles Bibliográficos
Autores principales: Maja Petkovic, Juan Oses-Prieto, Alma Burlingame, Lily Yeh Jan, Yuh Nung Jan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/e026443ef1f54cb589f59433ef9e4058
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e026443ef1f54cb589f59433ef9e4058
record_format dspace
spelling oai:doaj.org-article:e026443ef1f54cb589f59433ef9e40582021-12-02T18:18:36ZTMEM16K is an interorganelle regulator of endosomal sorting10.1038/s41467-020-17016-82041-1723https://doaj.org/article/e026443ef1f54cb589f59433ef9e40582020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17016-8https://doaj.org/toc/2041-1723The endolysosomal pathway plays an important role in regulating protein and lipid sorting and degradation. Here, the authors show that TMEM16K, an endoplasmic reticulum lipid scramblase, forms ER-endosome contact sites where it regulates endosomal sorting.Maja PetkovicJuan Oses-PrietoAlma BurlingameLily Yeh JanYuh Nung JanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maja Petkovic
Juan Oses-Prieto
Alma Burlingame
Lily Yeh Jan
Yuh Nung Jan
TMEM16K is an interorganelle regulator of endosomal sorting
description The endolysosomal pathway plays an important role in regulating protein and lipid sorting and degradation. Here, the authors show that TMEM16K, an endoplasmic reticulum lipid scramblase, forms ER-endosome contact sites where it regulates endosomal sorting.
format article
author Maja Petkovic
Juan Oses-Prieto
Alma Burlingame
Lily Yeh Jan
Yuh Nung Jan
author_facet Maja Petkovic
Juan Oses-Prieto
Alma Burlingame
Lily Yeh Jan
Yuh Nung Jan
author_sort Maja Petkovic
title TMEM16K is an interorganelle regulator of endosomal sorting
title_short TMEM16K is an interorganelle regulator of endosomal sorting
title_full TMEM16K is an interorganelle regulator of endosomal sorting
title_fullStr TMEM16K is an interorganelle regulator of endosomal sorting
title_full_unstemmed TMEM16K is an interorganelle regulator of endosomal sorting
title_sort tmem16k is an interorganelle regulator of endosomal sorting
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e026443ef1f54cb589f59433ef9e4058
work_keys_str_mv AT majapetkovic tmem16kisaninterorganelleregulatorofendosomalsorting
AT juanosesprieto tmem16kisaninterorganelleregulatorofendosomalsorting
AT almaburlingame tmem16kisaninterorganelleregulatorofendosomalsorting
AT lilyyehjan tmem16kisaninterorganelleregulatorofendosomalsorting
AT yuhnungjan tmem16kisaninterorganelleregulatorofendosomalsorting
_version_ 1718378247489585152