TMEM16K is an interorganelle regulator of endosomal sorting

The endolysosomal pathway plays an important role in regulating protein and lipid sorting and degradation. Here, the authors show that TMEM16K, an endoplasmic reticulum lipid scramblase, forms ER-endosome contact sites where it regulates endosomal sorting.

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Bibliographic Details
Main Authors: Maja Petkovic, Juan Oses-Prieto, Alma Burlingame, Lily Yeh Jan, Yuh Nung Jan
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/e026443ef1f54cb589f59433ef9e4058
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