Hybrid approach for predicting coreceptor used by HIV-1 from its V3 loop amino acid sequence.

<h4>Background</h4>HIV-1 infects the host cell by interacting with the primary receptor CD4 and a coreceptor CCR5 or CXCR4. Maraviroc, a CCR5 antagonist binds to CCR5 receptor. Thus, it is important to identify the coreceptor used by the HIV strains dominating in the patient. In past, a...

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Bibliographic Details
Main Authors: Ravi Kumar, Gajendra P S Raghava
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/e02801e0573948c0947001f0178e783c
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