PHYRN: a robust method for phylogenetic analysis of highly divergent sequences.

PHYRN: a robust method for phylogenetic analysis of highly divergent sequences.

Both multiple sequence alignment and phylogenetic analysis are problematic in the "twilight zone" of sequence similarity (≤ 25% amino acid identity). Herein we explore the accuracy of phylogenetic inference at extreme sequence divergence using a variety of simulated data sets. We evaluate...

Full description

Saved in:
Bibliographic Details
Main Authors: Gaurav Bhardwaj, Kyung Dae Ko, Yoojin Hong, Zhenhai Zhang, Ngai Lam Ho, Sree V Chintapalli, Lindsay A Kline, Matthew Gotlin, David Nicholas Hartranft, Morgen E Patterson, Foram Dave, Evan J Smith, Edward C Holmes, Randen L Patterson, Damian B van Rossum
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e03936a828f541d5a836cf69de48e3f6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/e03936a828f541d5a836cf69de48e3f6

Similar Items