High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility

Abstract Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. HPV is epitheliotropic and its replication is tightly associated with terminal keratinocyte differentiation making production and purification of high titer virus preparations for research...

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Autores principales: Daniel J. Goetschius, Samantha R. Hartmann, Suriyasri Subramanian, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e04b64485e644667b0e59a3751e54ebe
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