Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

Abstract Human malaria affects the vast majority of the world’s population with the Plasmodium falciparum species causing the highest rates of morbidity and mortality. With no licensed vaccine and leading candidates achieving suboptimal protection in the field, the need for an effective immunoprophy...

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Autores principales: Katherine L. Mallory, Justin A. Taylor, Xiaoyan Zou, Ishita N. Waghela, Cosette G. Schneider, Michael Q. Sibilo, Neeraja M. Punde, Leah C. Perazzo, Tatyana Savransky, Martha Sedegah, Sheetij Dutta, Chris J. Janse, Norbert Pardi, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Evelina Angov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/e05bb1dcc8a24bf8950c79ee7ff517fc
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https://doaj.org/article/e05bb1dcc8a24bf8950c79ee7ff517fc

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