Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1
P-glycoprotein, an ATP-binding cassette (ABC) transporter, extrudes a large variety of xenobiotics from the cell which protects tissues from toxins. Here authors solve a pair of X-ray structures of homodimeric P-glycoprotein and resolve structural elements proposed to participate in the mechanism of...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/e070bd814c674886ba6ba882b1f3a452 |
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