Do mechanisms matter? Comparing cancer treatment strategies across mathematical models and outcome objectives

When eradication is impossible, cancer treatment aims to delay the emergence of resistance while minimizing cancer burden and treatment. Adaptive therapies may achieve these aims, with success based on three assumptions: resistance is costly, sensitive cells compete with resistant cells, and therapy...

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Autores principales: Cassidy K. Buhler, Rebecca S. Terry, Kathryn G. Link, Frederick R. Adler
Formato: article
Lenguaje:EN
Publicado: AIMS Press 2021
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Acceso en línea:https://doaj.org/article/e0862ec0d0e14371aebb832f131c4a0d
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