Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses
ABSTRACT Human noroviruses (HuNoV) are a leading cause of viral gastroenteritis worldwide and a significant cause of morbidity and mortality in all age groups. The recent finding that HuNoV can be propagated in B cells and mucosa-derived intestinal epithelial organoids (IEOs) has transformed our abi...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/e094082be0f14373847279071b1750d4 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|