Dynamics of the major histocompatibility complex class I processing and presentation pathway in the course of malaria parasite development in human hepatocytes: implications for vaccine development.
Control of parasite replication exerted by MHC class I restricted CD8+ T-cells in the liver is critical for vaccination-induced protection against malaria. While many intracellular pathogens subvert the MHC class I presentation machinery, its functionality in the course of malaria replication in hep...
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Auteurs principaux: | Jinxia Ma, Stefanie Trop, Samantha Baer, Elian Rakhmanaliev, Zita Arany, Peter Dumoulin, Hao Zhang, Julia Romano, Isabelle Coppens, Victor Levitsky, Jelena Levitskaya |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Sujets: | |
Accès en ligne: | https://doaj.org/article/e09d1355f11a4c29833e9b05d5fca36d |
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