The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.

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Autores principales: Christina Ernst, Duncan T. Odom, Claudia Kutter
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/e0b3b4ef728c435a8cd07bd60478597a
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