The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.

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Detalles Bibliográficos
Autores principales:	Christina Ernst, Duncan T. Odom, Claudia Kutter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e0b3b4ef728c435a8cd07bd60478597a
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spelling	oai:doaj.org-article:e0b3b4ef728c435a8cd07bd60478597a2021-12-02T14:41:58ZThe emergence of piRNAs against transposon invasion to preserve mammalian genome integrity10.1038/s41467-017-01049-72041-1723https://doaj.org/article/e0b3b4ef728c435a8cd07bd60478597a2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01049-7https://doaj.org/toc/2041-1723Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.Christina ErnstDuncan T. OdomClaudia KutterNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christina Ernst Duncan T. Odom Claudia Kutter The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
description	Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.
format	article
author	Christina Ernst Duncan T. Odom Claudia Kutter
author_facet	Christina Ernst Duncan T. Odom Claudia Kutter
author_sort	Christina Ernst
title	The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
title_short	The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
title_full	The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
title_fullStr	The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
title_full_unstemmed	The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
title_sort	emergence of pirnas against transposon invasion to preserve mammalian genome integrity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e0b3b4ef728c435a8cd07bd60478597a
work_keys_str_mv	AT christinaernst theemergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity AT duncantodom theemergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity AT claudiakutter theemergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity AT christinaernst emergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity AT duncantodom emergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity AT claudiakutter emergenceofpirnasagainsttransposoninvasiontopreservemammaliangenomeintegrity
_version_	1718389841991827456

The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity

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