The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity
Transposable elements can be activated during germ cell maturation, potentially leading to genome instability and rewiring of the genetic circuitry. In this review, the authors discuss how the piRNA machinery suppresses these elements to ensure accurate spermatogenesis.
Guardado en:
Autores principales: | Christina Ernst, Duncan T. Odom, Claudia Kutter |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e0b3b4ef728c435a8cd07bd60478597a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Endogenous Viral Element-Derived Piwi-Interacting RNAs (piRNAs) Are Not Required for Production of Ping-Pong-Dependent piRNAs from Diaphorina citri Densovirus
por: Jared C. Nigg, et al.
Publicado: (2020) -
PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice
por: Deqiang Ding, et al.
Publicado: (2017) -
piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm
por: Jérémy Dufourt, et al.
Publicado: (2017) -
TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice
por: Deqiang Ding, et al.
Publicado: (2018) -
Arbovirus-derived piRNAs exhibit a ping-pong signature in mosquito cells.
por: Nicolas Vodovar, et al.
Publicado: (2012)