ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens

ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens

The generation of protective secretory IgA is a desired outcome of oral vaccination. Here, the authors show that the depletion of intestinal ATP significantly improves the production and response of high-affinity IgA against both live and inactivated oral vaccines.

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Detalles Bibliográficos
Autores principales: Michele Proietti, Lisa Perruzza, Daniela Scribano, Giovanni Pellegrini, Rocco D’Antuono, Francesco Strati, Marco Raffaelli, Santiago F. Gonzalez, Marcus Thelen, Wolf-Dietrich Hardt, Emma Slack, Mauro Nicoletti, Fabio Grassi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/e0e24831b05347f7a1b912b1db0a67fd
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https://doaj.org/article/e0e24831b05347f7a1b912b1db0a67fd

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