COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways....

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Bibliographic Details
Main Authors: Gita Naseri, Jessica Behrend, Lisa Rieper, Bernd Mueller-Roeber
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
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Online Access:https://doaj.org/article/e10acb88f20e410785c3689d2c7e5b19
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