COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways....

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Autores principales:	Gita Naseri, Jessica Behrend, Lisa Rieper, Bernd Mueller-Roeber
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e10acb88f20e410785c3689d2c7e5b19
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spelling	oai:doaj.org-article:e10acb88f20e410785c3689d2c7e5b192021-12-02T14:38:47ZCOMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors10.1038/s41467-019-10224-x2041-1723https://doaj.org/article/e10acb88f20e410785c3689d2c7e5b192019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10224-xhttps://doaj.org/toc/2041-1723Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways.Gita NaseriJessica BehrendLisa RieperBernd Mueller-RoeberNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gita Naseri Jessica Behrend Lisa Rieper Bernd Mueller-Roeber COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
description	Metabolic engineering requires the balancing of gene expression to obtain optimal output. Here the authors present COMPASS – COMbinatorial Pathway ASSembly – which uses plant-derived artificial transcription factors and cloning of thousands of DNA constructs in parallel to rapidly optimise pathways.
format	article
author	Gita Naseri Jessica Behrend Lisa Rieper Bernd Mueller-Roeber
author_facet	Gita Naseri Jessica Behrend Lisa Rieper Bernd Mueller-Roeber
author_sort	Gita Naseri
title	COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
title_short	COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
title_full	COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
title_fullStr	COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
title_full_unstemmed	COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
title_sort	compass for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e10acb88f20e410785c3689d2c7e5b19
work_keys_str_mv	AT gitanaseri compassforrapidcombinatorialoptimizationofbiochemicalpathwaysbasedonartificialtranscriptionfactors AT jessicabehrend compassforrapidcombinatorialoptimizationofbiochemicalpathwaysbasedonartificialtranscriptionfactors AT lisarieper compassforrapidcombinatorialoptimizationofbiochemicalpathwaysbasedonartificialtranscriptionfactors AT berndmuellerroeber compassforrapidcombinatorialoptimizationofbiochemicalpathwaysbasedonartificialtranscriptionfactors
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COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors

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