Predicting the frequencies of drug side effects

Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.

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Autores principales: Diego Galeano, Shantao Li, Mark Gerstein, Alberto Paccanaro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b
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spelling oai:doaj.org-article:e13f5df0401d4c95ac1e4ea0421f663b2021-12-02T17:41:08ZPredicting the frequencies of drug side effects10.1038/s41467-020-18305-y2041-1723https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18305-yhttps://doaj.org/toc/2041-1723Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.Diego GaleanoShantao LiMark GersteinAlberto PaccanaroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Diego Galeano
Shantao Li
Mark Gerstein
Alberto Paccanaro
Predicting the frequencies of drug side effects
description Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.
format article
author Diego Galeano
Shantao Li
Mark Gerstein
Alberto Paccanaro
author_facet Diego Galeano
Shantao Li
Mark Gerstein
Alberto Paccanaro
author_sort Diego Galeano
title Predicting the frequencies of drug side effects
title_short Predicting the frequencies of drug side effects
title_full Predicting the frequencies of drug side effects
title_fullStr Predicting the frequencies of drug side effects
title_full_unstemmed Predicting the frequencies of drug side effects
title_sort predicting the frequencies of drug side effects
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b
work_keys_str_mv AT diegogaleano predictingthefrequenciesofdrugsideeffects
AT shantaoli predictingthefrequenciesofdrugsideeffects
AT markgerstein predictingthefrequenciesofdrugsideeffects
AT albertopaccanaro predictingthefrequenciesofdrugsideeffects
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