Predicting the frequencies of drug side effects

Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.

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Détails bibliographiques
Auteurs principaux:	Diego Galeano, Shantao Li, Mark Gerstein, Alberto Paccanaro
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b
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spelling	oai:doaj.org-article:e13f5df0401d4c95ac1e4ea0421f663b2021-12-02T17:41:08ZPredicting the frequencies of drug side effects10.1038/s41467-020-18305-y2041-1723https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18305-yhttps://doaj.org/toc/2041-1723Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.Diego GaleanoShantao LiMark GersteinAlberto PaccanaroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diego Galeano Shantao Li Mark Gerstein Alberto Paccanaro Predicting the frequencies of drug side effects
description	Currently, the frequencies of drug side effects are determined in randomised controlled clinical trials. Here the authors develop an interpretable machine learning approach to predict the frequencies of unknown side effects for drugs with a small number of determined side effect frequencies.
format	article
author	Diego Galeano Shantao Li Mark Gerstein Alberto Paccanaro
author_facet	Diego Galeano Shantao Li Mark Gerstein Alberto Paccanaro
author_sort	Diego Galeano
title	Predicting the frequencies of drug side effects
title_short	Predicting the frequencies of drug side effects
title_full	Predicting the frequencies of drug side effects
title_fullStr	Predicting the frequencies of drug side effects
title_full_unstemmed	Predicting the frequencies of drug side effects
title_sort	predicting the frequencies of drug side effects
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e13f5df0401d4c95ac1e4ea0421f663b
work_keys_str_mv	AT diegogaleano predictingthefrequenciesofdrugsideeffects AT shantaoli predictingthefrequenciesofdrugsideeffects AT markgerstein predictingthefrequenciesofdrugsideeffects AT albertopaccanaro predictingthefrequenciesofdrugsideeffects
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Predicting the frequencies of drug side effects

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